That's my neighborhood and there are countless places to go. Here a few suggestions that are reasonably priced (some more than others - so check out the Zagat links to the right):
Charming/Quaint: The Popover Cafe, Good Enough To Eat. Sarabeth's
French Cafe: Le Pain Quotidien
Italian: Isabella's
Jewish Deli: Barney Greengrass
If you are going for a weekend brunch I would suggest an early start as all these place get very crowded.
À votre santé